The large breadth of coverage provided by this facility enables comprehensive services in epigenetics, genomics, and gene expression.
Epigenetics
IBX utilizes cutting edge microarray and Next-Generation Sequencing platforms to achieve genome-wide detection of epigenetic events.
- Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix Genotyping products
- Illumina MiSeq Personal Sequencer produces 8.5 Gb of high-quality sequence data in less than 40 hours
- Illumina HiSeq 2000 provides industry leading sequencing throughput (600Gb in a single run)
Genomics
IBX has a fully automated robotics facility for production of custom DNA formats, SNP and microsatellite genotyping, Next Generation sequencing, and genetic testing.
- ABI 7900HT – This quantitative PCR system combines 96- and 384-well formats with fully automated robotic loading and fast real-time PCR capability.
- ViiA™ 7 instruments – This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation for high-productivity real-time PCR processing.
- Fluidigm BioMark™ System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 genotypes in picoliter volumes in 90 min.
- Wafergen™ SmartChip catalog and MyDesign™ Arrays – capable of 5000+ genotypes in any sample or assay format desired.
- Beckman Coulter GenomeLab SNPstream™ Genotyping System – capable of performing from 4,600 to over 3,000,000 SNP genotypes per day.
- Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix Genotyping products
- Illumina iScan Systems for all Illumina Genotyping products.
- NuGEN Mondrian and Caliper SciClone systems for fully automated construction of sequencing libraries
- Ion Torrent Semiconductor sequencing on the Ion Personal Genome Machine (PGM). 314, 316 and 318 chips produce up to 10Mb, 100Mb and 1Gb of raw sequence data in less than 5 hours
- Illumina MiSeq Personal Sequencer produces 8.5 Gb of high-quality sequence data in less than 40 hours
- Illumina HiSeq 2000 provides industry leading sequencing throughput (600Gb in a single run)
Gene Expression
IBX’s analytical facilities include instrumentation capable of low to medium and high throughput microarray-based solutions for gene profiling studies.
- Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix gene profiling products
- Illumina iScan System for all Illumina microarray products
- Agilent CGH arrays, Invitrogen NCode arrays
- Applied Biosystems ViiA™ 7 Real-Time PCR System- This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation. This system combines 96 and 384-well formats with fully automated robotic plate loading for high-productivity real-time PCR processing.
- Fluidigm BioMark™ System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 real-time qPCR reactions in picoliter volumes in a single run. Digital PCR arrays enable ultrahigh-resolution and absolute molecule quantification for gene copy number experiments.
- Wafergen™ SmartChip Catalogue and MyDesign™ Arrays – capable of 5000+ real-time qPCR reactions with flexible sample and assay formats.
