Analytical Facilities
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The analytical facilities at IBX Infinite Biologics are comprised of a variety of instrumentation that utilize cutting-edge technologies

Infinity BiologiX Analytical Facilities

The large breadth of coverage provided by this facility enables comprehensive services in epigenetics, genomics, and gene expression.


Epigenetics

IBX utilizes cutting edge microarray and Next-Generation Sequencing platforms to achieve genome-wide detection of epigenetic events.

  • Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix Genotyping products
  • Illumina MiSeq Personal Sequencer produces 8.5 Gb of high-quality sequence data in less than 40 hours
  • Illumina HiSeq 2000 provides industry leading sequencing throughput (600Gb in a single run)

Genomics

IBX has a fully automated robotics facility for production of custom DNA formats, SNP and microsatellite genotyping, Next Generation sequencing, and genetic testing.

  • ABI 7900HT – This quantitative PCR system combines 96- and 384-well formats with fully automated robotic loading and fast real-time PCR capability.
  • ViiA™ 7 instruments – This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation for high-productivity real-time PCR processing.
  • Fluidigm BioMark™ System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 genotypes in picoliter volumes in 90 min.
  • Wafergen™ SmartChip catalog and MyDesign™ Arrays – capable of 5000+ genotypes in any sample or assay format desired.
  • Beckman Coulter GenomeLab SNPstream™ Genotyping System – capable of performing from 4,600 to over 3,000,000 SNP genotypes per day.
  • Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix Genotyping products
  • Illumina iScan Systems for all Illumina Genotyping products.
  • NuGEN Mondrian and Caliper SciClone systems for fully automated construction of sequencing libraries
  • Ion Torrent Semiconductor sequencing on the Ion Personal Genome Machine (PGM). 314, 316 and 318 chips produce up to 10Mb, 100Mb and 1Gb of raw sequence data in less than 5 hours
  • Illumina MiSeq Personal Sequencer produces 8.5 Gb of high-quality sequence data in less than 40 hours
  • Illumina HiSeq 2000 provides industry leading sequencing throughput (600Gb in a single run)

Gene Expression

IBX’s analytical facilities include instrumentation capable of low to medium and high throughput microarray-based solutions for gene profiling studies.

  • Affymetrix GeneChip® and GeneTitan® Systems for all Affymetrix gene profiling products
  • Illumina iScan System for all Illumina microarray products
  • Agilent CGH arrays, Invitrogen NCode arrays
  • Applied Biosystems ViiA™ 7 Real-Time PCR System- This high performance instrument delivers exceptional reproducibility with minimal well-to-well and instrument-to-instrument variation. This system combines 96 and 384-well formats with fully automated robotic plate loading for high-productivity real-time PCR processing.
  • Fluidigm BioMark™ System using 96.96 and 48.48 Dynamic Arrays – capable of 9,200 real-time qPCR reactions in picoliter volumes in a single run. Digital PCR arrays enable ultrahigh-resolution and absolute molecule quantification for gene copy number experiments.
  • Wafergen™ SmartChip Catalogue and MyDesign™ Arrays – capable of 5000+ real-time qPCR reactions with flexible sample and assay formats.

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